Losartan Side Effects In Summary. Select one or more newsletters to continue. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use losartan only for the indication prescribed. Loss Of Appetite 7. This medication is available as an oral tablet and may also come with the brand name Cozaar on the label. It is not a cure for the condition, simply a way to manage it. We're open with COVID-19 protocols and testing, Worried about your substance use? Side effects for those suffering from Losartan are not very common. The antihypertensive effect of losartan was more pronounced and homogeneous than the effect of an equivalent dose of captopril. The first chemical dependency recovery hospital in the OC, we offer safe medical detox, mental health support, and wellness programs. Indigestion 6. Losartan. Combining losartan with any of these does not improve effectiveness, but it does increase the probability of side effects. The dosage of losartan may need reducing in people with liver disease. Even though losartan is not a significant drug of abuse, any individual who has been taking the drug should only discontinue it under the supervision of a physician and according to their physician’s instructions. Patients taking Losartan for high blood pressure also report fatigue as a side effect. Our editors and medical reviewers have over a decade of cumulative experience in medical content editing and have reviewed...Read More. Blocking angiotensin II widens (dilates) blood vessels which lowers blood pressure. If you do inadvertently become pregnant, tell your doctor immediately. amlodipine, metoprolol, lisinopril, furosemide, hydrochlorothiazide, atenolol, enalapril, irbesartan, ramipril, benazepril. This phenomenon is known as the “nocebo effect,” the opposite of the placebo effect. Stop taking losartan if you become pregnant and call your doctor right away. Copyright 1996-2021 Drugs.com. May increase potassium levels in the body. However, according to professional sources such as the book Pharmacology of Antihypertensive Drugs, suddenly discontinuing the drug can lead to a rapid increase in blood pressure that can increase the risk for: Abruptly stopping antihypertensive medications may also result in some other effects that are often labeled as withdrawal issues when they occur with other medications, but technically, they are not labeled as withdrawal issues by professional sources when they occur with antihypertensive medications because they are not associated with drug-seeking behaviors and cravings for antihypertensive drugs. Heavy media coverage of statins may also lead people to stop taking them, according to a study from the UK. Black, tarry stools 2. blood in the urine or stools 3. cough or hoarseness accompanied by chills or fever, lower back or side pain, or painful or difficult urination 4. fainting 5. pinpoint red spots on the skin 6. pounding heartbeat 7. severe stomach pain, nausea, and vomiting 8. skin rash 9. swelling of the feet or lower legs 10. unusual bleeding or bruising You can take your doses either before or after a meal. Other than that, I am very pleased with this medication. What is losartan used for? Losartan/hydrochlorothiazide can cause mild or serious side effects. https://lagunatreatment.com/drug-abuse/losartan/withdrawal-symptoms When pregnancy is detected, discontinue losartan as soon as possible. Can be administered with or without food. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Losartan has generally received positive reviews regarding its effectiveness as a medication, and it is not considered to be a potential drug of abuse. Diarrhea, tiredness, and low blood sugar have also reported in people with type 2 diabetes taking losartan. This drug is more popular than comparable drugs. Losartan is a type of drug called a sartan that works by stopping a hormone called angiotensin II from activating a receptor in the body, which normally leads to a slight increase in blood pressure. Losartan belongs to a group of medicines known as angiotensin II receptor blockers (which may be shortened to ARBs). Ensure adequate contraception is used when prescribing to women of child-bearing age. Drugs that act directly on the... For Healthcare Professionals. View complete list of side effects. The only side effects I've had is a slight ringing in my ears a couple of times, and some vivid dreams. Losartan Side Effects. Your doctor may require you to see him or her regularly for monitoring of your blood pressure, kidney function, or electrolytes. The time to peak effect after a dose is 1-2 hours for losartan and 3-4 hours for the metabolite. Losartan also increases the excretion of certain salts from the kidney. Losartan is metabolized in the liver to an active metabolite (which has a similar action to losartan). If experienced, these tend to have a Severe expression 1. People using losartan should not drink alcohol or use other substances that can further lower their blood pressure because this can lead to significant issues with hypotension (low blood pressure) that can be potentially dangerous. Some people who take Losartan may experience side effects. 39 In rats with aortic coarctation, 2-week administration of losartan at a sub-antihypertensive dose of 3 mg/kg per day reduced ACE expression and ACE activity to the level of sham-operated animals, a mechanism that might also result in decreased bradykinin breakdown. losartan can harm your unborn baby causing injury and even death. Lowering blood pressure has been shown to decrease the risk of fatal and nonfatal cardiovascular events (such as a heart attack or stroke). Losartan/hctz is an inexpensive drug used to treat high blood pressure.This medicine may also reduce the risk of stroke in certain patients. Your doctor may prescribe losartan if you've tried taking similar blood pressure-lowering medicines such as ramipril and lisinopril in the past, but had to stop taking them because of side effects such as a dry, irritating cough. Losartan may be used for the treatment of high blood pressure or certain types of … Druginformer Identified Side Effects: Fatigue, Somnolence, Arthralgia, Incontinence, Anxiety, Discomfort, Cough, Palpitations, Depression. Call us for help. The following list contains some of the key side effects that may occur while taking losartan. Losartan Side Effects. We comply with the HONcode standard for trustworthy health information -, Drug class: angiotensin receptor blockers. Losartan is available as a generic and as the brand name Cozaar. The appearance of physical and even psychological issues with the sudden discontinuation of losartan and not labeling them as a formal type of withdrawal syndrome is reminiscent of the denial by various medical associations regarding the discontinuation of antidepressant medications, which are drugs that are also not significant drugs of abuse like antihypertensive medications. An interaction between two medications does not always mean that you must stop taking one of the medications; however, sometimes it does. Throat Irritation 11. These are some of the most common side effects: – Diarrhea: Some people may notice diarrhea immediately after stopping losartan. All rights reserved. May not be as effective in people of African-American descent. Our editors and medical reviewers have over a decade of cumulative experience in medical content editing and have reviewed... © 2021 American Addiction Centers. Ensure you are adequately hydrated before starting this medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Answered by Dr. Edward Hirsch: Maybe: Losartan can cause cough. Nonetheless, some of these issues include: Thus, when the drug is discontinued, it is typically done on a tapering schedule to wean the person off the medication and avoid these potential issues. This claim by various medical associations, including APA, continued for quite some time until a formal syndrome was identified as a result of the discontinuation of these medications in a small percentage of individuals. It is most often referred to as an antidepressant discontinuation syndrome, which can be avoided by use of a tapering schedule. Rarely, may cause angioedema (this is a swelling of the deeper layers of the skin which can be life-threatening if it affects the throat). Take losartan once each day. Should not be used during pregnancy. This site complies with the HONcode standard for trustworthy health information: verify here. Blood Pressure Drop Upon Standing 3. Low Energy 9. There is no category for antihypertensive abuse listed by the National Institute on Drug Abuse (NIDA), the Substance Abuse and Mental Health Services Administration (SAMHSA), the American Psychiatric Association (APA), the American Society of Addiction Medicine (ASAM), etc. Note that this list is not all-inclusive and includes only common medications that may interact with losartan. May be administered with other drugs that are also used to lower blood pressure (such as diuretics). It is available in brand and generic form. United States Drug Enforcement Administration (DEA), Substance Abuse and Mental Health Services Administration (SAMHSA), American Society of Addiction Medicine (ASAM), effects that are often labeled as withdrawal issues, Lightheadedness, dizziness, and confusion, Swelling, particularly in the legs or ankles. Losartan is not listed as a controlled substance by the United States Drug Enforcement Administration (DEA). It is typically prescribed to treat hypertension in a variety of situations, and it is effective for these uses. Second, a direct effect of losartan on aortic ACE expression and activity has been suggested. As with any medication, Losartan use comes with the chance of developing side effects. Numerous studies have failed to document significant withdrawal symptoms in people prescribed the drug who have suddenly discontinued its use. May interact with a number of other drugs including NSAIDs, lithium, and potassium supplements. You should refer to the prescribing information for losartan for a complete list of interactions. These side effects are not serious and will only need to be reported to your doctor if they begin to interfere with your ability to func… If a woman inadvertently becomes pregnant while taking losartan, it should be immediately discontinued. "if my losartan is causing me to cough should i stop taking it?" antipsychotic agents (may enhance the blood pressure-lowering effect), such as aripiprazole or clozapine, NSAIDs, such as ibuprofen, diclofenac, or naproxen, other ARBs (such as candesartan or irbesartan) or ACE inhibitors (such as captopril or lisinopril), phosphodiesterase-5-inhibitors, such as sildenafil, sedatives, such as temazepam and zolpidem. Losartan may cause fatigue 2. In the RENAAL study -- a premarketing study -- 14 percent of the 1,513 participants reported feelings of fatigue. Abnormally Low Blood Pressure 2. Limit alcohol intake while you are taking losartan. Losartan may be used for the treatment of high blood pressure or certain types of kidney disease. Feel Like Throwing Up 5. Other side effects reported more commonly include dizziness in up to 3 percent of users, nasal congestion in 2 percent and back pain in 2 percent of patients. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Losartan may cause a drop in blood pressure, especially when going from a sitting or lying down position to standing. Recall of Blood Pressure Medication Losartan Expands Over Cancer Concerns. People whose renal function is dependant on the activity of the renin-angiotensin system (which includes the hormone angiotensin II), such as people with renal artery stenosis, chronic kidney disease, severe congestive heart failure, or who are dehydrated are more at risk. Revision date: March 19, 2020. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. ... taking a beta blocker for hbp for about 6 months but have side effects dr told me to take losartan and stop beta safe to … This randomized, double-blind, parallel-group, multicenter study compared the efficacy of amlodipine and losartan in an older hypertensive population, focusing on therapeutic coverage in the case of missed doses. The dosage of losartan may need adjusting depending on how you respond to it. Laguna is taking every precaution to ensure patient and staff safety. Commonly reported side effects of losartan include: asthenia, chest pain, diarrhea, fatigue, and... For the Consumer. To make sure losartan is safe for you, tell your doctor if you: This may make you feel dizzy and increase your risk of falling over. Losartan is primarily used to treat high blood pressure. Cozaar (losartan) is an antihypertensive medication. Losartan may need to be withheld or discontinued in people who develop a significant decrease in kidney function. Losartan is a prescription medication used for the treatment of conditions to do with blood pressure. The most regularly reported side effect of this medication is an increase in infections such as colds or the flu which occurs in up to 8 percent of users. Laguna Treatment Hospital is located in Orange County, CA. Thus, losartan may be a drug that is prescribed to individuals with substance use disorders; however, there is no recognized literature that suggests that it is a significant drug of abuse itself, that its use fosters some other forms of drug abuse, or that it is a potential substance that individuals who are in recovery will use during relapse for its psychoactive effects. It is classified as an angiotensin II receptor agonist, and its use leads to blood vessels not constricting and lowered blood pressure. Renal function should be monitored periodically in these people. Starting recovery at Laguna is life changing. Following a 4-week, single-blind, placebo washout period, 211 patients were randomly as … People being initiated on losartan should be adequately rehydrated and have normal electrolyte levels. If you forget to take your dose, take it as soon as you remember that day. It may take up to a week for significant blood pressure lowering or kidney effects are noted, with maximal effects occurring in 3 to 6 weeks. Talk to your doctor if this happens to you. Still, this syndrome is not referred to as a formal withdrawal syndrome. Available for Android and iOS devices. Losartan can cause mild or serious side effects. Visible Water Retention Alcohol can increase your chance of side effects such as dizziness and lightheadedness. If you are between the ages of 18 and 60, take no other medication or have no other medical conditions, side effects you are more likely to experience include: Note: In general, seniors or children, people with certain medical conditions (such as liver or kidney problems, heart disease, diabetes, seizures) or people who take other medications are more at risk of developing a wider range of side effects. When you take irbesartan, the hormone can’t work as well as usual and your blood pressure gets lower as a result. Low Blood Sugar 8. Editorial Staff, American Addiction Centers, The editorial staff of Laguna Treatment Hospital is comprised of addiction content experts from American Addiction Centers. Let us help you get started with the rest of your life! Stomach Cramps 10. Generally, should not be prescribed with potassium supplements or other medicines that retain potassium. The group-average trough/peak ratios upon the losartan treatment were 61.5 and 61.3% for the systolic and diastolic BP (against 21.2 and 26.9% for captopril), respectively. We remain open and committed to supporting your recovery journey. Some painkillers can interfere with losartan and increase the risk of side-effects, so ask a pharmacist for advice before you buy any medicines 'over the counter'. Losartan may also be called an angiotensin II receptor antagonist. But, if it is nearly time for your next dose, just take the next dose at the right time. Losartan works by blocking the effect of angiotensin II, a hormone that causes blood vessels to narrow (constrict) increasing blood pressure. May be used in the treatment of kidney disease in people with type 2 diabetes with a history of high blood pressure and elevated laboratory markers. To your doctor if this happens to you not constricting and lowered blood pressure action comes amid ongoing of! 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